Officers from the Serious and Organised Crime Division stopped a vehicle on the Eyre Highway on Saturday morning. Police alleged that inside the vehicle they found six kilograms in ecstasy pills, 3.5 kilograms of heroin and almost 4 kilograms of cocaine.
A Kalgoorlie man, 35, has been charged with possessing a prohibited drug with intent to sell or supply in relation to the ecstasy pills.
He was refused bail when he appeared in the Kalgoorlie Magistrates Court and is due to reappear on Thursday.
Police said further charges were expected in relation to the heroin and cocaine.