Two people are dead and three injured after two separate crashes that occurred within an hour in Victoria’s north-west. The fatal crashes occurred about 50 kilometres apart on Thursday afternoon.

A truck driver was trapped in his rig for more than two hours, after it collided head-on with a truck on the Wimmera Highway at Marnoo East shortly after 1.30pm.

“It is believed the truck was travelling west when the oncoming car has veered onto the wrong side of the road and the two vehicles have collided,” a police spokesman said.

Sergeant Bill Alford told the Wimmera Mail-Times the driver of the car was thrown from the vehicle and died at the scene. Her male passenger has been flown to The Alfred hospital.

The male truck driver was trapped in his rig for more than two hours.

Country Fire Authority officer Ian Morley told the Wimmera Mail-Times the truck driver had two suspected broken legs. He was taken to the Horsham hospital.

About an hour later, two cars collided near Horsham at the intersection of Murtoa-Glenorchy Road and Horsham-Lubeck Road.

“It would appear one vehicle has failed to give way to the other,” a police spokeswoman said.

Little remains of one car, which burst into flames after the crash. The driver died at the scene.

The other driver has been taken to the Horsham hospital in a stable condition.

The Wimmera Highway is closed in both directions at McPherson Road and is not expected to reopen for some time.

Traffic diversions are in place.