Sources privy to police and rescue teams stated that the van was over-speeding which caused the accident.
Teams had to struggle to recover bodies of the victims from wrecked coach. Locals who were passing by and ambulances shifted bodies and injured to Civil Hospital.
Eye witnesses said that driver of the coach was killed in the accident however, police have launched investigations.
Around 15 days earlier, a speeding coach collided with a car at the Indus Highway in Khanpur near Shikarpur killing four people.
Rescue sources had said that the killed and wounded were members of a family who were travelling from Larkana to Kandh Kot.
Road accidents frequently happen in Pakistan due to poorly maintained roads, violation of road safety rules and reckless driving.
According to data compiled by Pakistan Bureau of Statistics, over 9,000 road accidents are reported to the police every year, killing on average around 5,000 people annually in the country.
Traffic police officials say that 90 percent of accidents in Pakistan are caused merely by human errors.