Police said their injures appear to be non-life threatening.
All three of the people involved are from the Trinity-Conception Bay area, police said.
An RCMP crash analyst was called to the scene to investigate.
The highway was closed to traffic at the time of the crash, but was since reopened. The Spaniard’s Bay and Seaside volunteer fire departments, along with Department of Transportation, assisted.
Anyone who may have witnessed the collision is asked to contact Bay Roberts RCMP.